The ZILOS-tk zona laser drill was featured in 11 abstracts presented at the ASRM Meeting, in Philadelphia, PA, October 16-20, 2004. The ZILOS-tk is quickly becoming the industry leader. Read the abstracts on the Hamilton Thorne Bisociences web site.
The ZILOS-tk features a Class 1 Laser integrated into a specially designed 50x objective and Isotherm Rings - the Original Embryo Safeguard! No other system gives you the ease of use, flexibility, and portability of the ZILOS-tk!
300 mW Laser Power and ONE Microsecond Pulse Length
The ZILOS-tk features a 300 mw laser and a pulse length as low as 1 microsecond, which is far lower than typical zona ablation procedures require.
The image at the right shows the size of the Isotherm Rings at a laser pulse setting of 100 microseconds (outer ring at 50°C safe zone). The orange ring shows the drill hole size.
Since the ZILOS-tkT laser is based on the standard objective height, it easily installs on turrets of all models of inverted microscopes, even older models . Also, the unique design of the laser allows unrestricted access to other installed objectives. And you can switch the ZILOS-tkT laser from one brand of microscope to another - without need of physical laser realignment or customization. In addition, the 50x magnification of the ZILOS-tk objective provides the highest magnification available on a zona drilling laser unit.
When working with micromanipulators, the ZILOS-tk allows you to work in "hands-free" mode by using the optional foot switch to fire the laser. Simply use the manipulators to position the embryo to the target and press the foot switch to fire the laser. Your micromanipulation proceeds rapidly and the time the embryo spends on the microscope stage is minimized. Also, under LOW the Clinical Energy setting, the laser may be fired up to 15 times in 15 seconds, without need of reactivating the laser (10 times at MEDIUM setting). There is also no need to use valuable time to draw the hole size on the monitor since the patent-pending Isotherm RingsT automatically show the hole diameter at every pulse and power combination.
The Flash movie loop at right shows how easy and fast it is to use the ZILOS-tk for zona drilling. (Requires Flash 6 or higher). Whether you use micromanipulators or the stage controls to position the embyo, the drilling process proceeds rapidly. (Video footage courtesy of Steven McArthur, Sydney IVF. All rights reserved.)
Free Your Microscope Ports
The ZILOS-tkT laser leaves both the fluorescent light port and the filter cube port open for normal use (Oosight™ compatible). Other laser systems use one of these ports to install their laser, which can interfere with full microscope functionality. The ZILOS-tk is the only laser system which doesn't require removal of the laser to use fluorescence.
The ZILOS-tk laser is physically aligned under strictly controlled conditions at the factory and locked in place, so you do not have to perform tedious alignment procedures on-site. Simply align the computer generated target to the laser spot and you are ready to go! Learn more about the importance of laser alignment on the Hamilton Thorne web iste.
For a complete laser system, including full featured software and computer, the portability of the ZILOS-tk laptop configuration can't be beat. All laser components fit into a custom designed carry case, which offers both protection and easy transport. Combine this with a laptop unit and a small digital camera, and you can literally walk out the door with a " ZILOS-tk To Go !"
Caution: Federal law restricts this device to sale by or on the order of a physician or a practitioner trained and certified in its use. Assisted Hatchling is not recommended for routine use in all IVF patients
The ZILOS-tk® for 
300 mW Laser Power and ONE Microsecond Pulse Length 
No jerky motion or image delay
