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IVOS Sperm Analyzer 
As the only sperm analysis system with an internal optical system, the IVOS offers distinct advantages to the sperm analysis laboratory. In contrast to the continuous illumination of a microscope, the IVOS uses illumination strobed at 1/1000 of a second to visualize sperm motion. This strobed illumination eliminates motion-related blurring along the length of the sperm head, resulting in precise sperm tracking. By adding an image capture rate of 60 frames per second, you get the highest level of accuracy available today for measuring sperm velocities and motion parameters. For added flexibility, the IVOS performs analyses under three types of internal, strobed illumination: phase contrast, bright field and multi-wavelength fluorescence. 
As part of the integrated optical system, the unique computer controlled specimen stage of the IVOS provides precise control of temperature and position during analysis. The stage temperature, which may be set from ambient to 40°C, remains constant to within 0.5°C. For selection of analysis fields, the stage may be programmed for either manual or automatic field selection. For at-a-glance monitoring, the current stage temperature and position are continuously shown on screen as a real-time, digital display. The IVOS stage accommodates and automatically adjusts for commonly used analysis chambers, such as disposable fixed-depth slides, cannulas and Makler chambers. In addition, a user-defined chamber setting is available| IVOS | CEROS |
| If high-end performance using the published standard is key for your lab, then the IVOS is the best option. | If you require the objectivity and accuracy of automated analysis, but at a more affordable price, then choose the CEROS. |
| All optics components built into one integrated workstation | External microscope allows computer to be stored under the lab bench to save space |
| Strobe illumination: provides sharpest imaging | Familiar, standard microscope illumination |
| Automated, built-in, heated stage for precise temperature control and sample positioning | Portable MiniTherm Stage Warmer maintains samples at 37°C |
| Preselection of fields for fastest analysis | X-Y stage movement increases number of fields available for motility and morphology |
| Required for optional IDENT fluorescence capability | Not compatible with IDENT fluorescence capability |
The IVOS hardware and software have been designed to provide users with a system that offers high-end performance while maintaining its ease of use. The intuitive Windows-based software promotes fast learning and quickly increases the confidence level of users. Since the settings for the integrated optics are made through the software, mechanical adjustments are rarely required. With a minimum investment of time, even users unfamiliar with computers will be performing fast, accurate and reliable sperm analyses. You don’t need to be a computer expert to analyze sperm with the IVOS.
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Redesigned software interface of Version 12 makes operation intuitive
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Up to 7 analysis setups (including optic calibrations) may be stored to memory and selected at the touch of a button
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Patient and sample information easily entered from keyboard
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Simply place the sample chamber on the stage, focus the image, select the fields, and begin analysis
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On-site customized installation and training provided with all new systems
Results You Need
Whether you need basic counts and motilities or detailed analysis of sperm motion, the IVOS provides you with the results you need. Results for motile, progressively motile and static sperm include actual number counted, sample total, concentrations and percentages. Additional results include averages and distribution bar charts of velocities, motion characteristic and morphometry.
Samples of all results screens are available under Sample Screens.
Real-Time Quality Control
The IVOS provides on demand quality control with the Playback feature. Using image Playback, the accuracy of the analysis is confirmed. To optimize the system, analysis parameters may be adjusted using the two interactive QC Plots or directly from the analysis setup screen.
Summary of Results Provided
- Counts:
- Total, Motile, Progressive
- % Motile, % Progressively Motile
- Rapid, Medium, Slow and Static Cells
- Concentrations
- Total, Motile, Progressive (millions/ml)
- Rapid, Medium, Slow and Static Cells (millions/ml)
- Mean Values
- VAP: Smoothed Path Velocity (microns/sec)
- VCL: Track Velocity (microns/sec)
- VSL: Straight Line Velocity (microns/sec)
- ALH: Amplitude of Lateral Head Displacement (microns)
- BCF: Beat Cross Frequency (hertz)
- LIN: Linearity (ratio of VSL/VCL)
- STR: Straightness (ratio of VSL/VAP)
- Elongation: head shape (ratio of minor to major axis of sperm head)
- Area: head size (square microns)
- Bar Chart Distributions
- VAP, VCL, VSL, Elongation, ALH, BCF, LIN, STR
See the Hamilton Thorne Biosciences Web Site for Information on Options and Customer Profiles
